Wednesday, July 21, 2004

Citrina Summary

"Citrina (pronounced sih-TREE-nuh) is a database management tool that automates the mirroring and processing of databases that are distributed via ftp servers. It is built around the Ant java build tool making it very flexible and portable. Citrina only provides the basic functionality for mirroring but can easily be extended to do other tasks. For example, with Citrina you could mirror the uniprot database to your local system, generate fasta files, create the blast dbs, and run blast on a set of proteins you are interested in."

Have to keep this in mind for possible automization protocols

Saturday, July 17, 2004

Thursday, July 15, 2004

MacDevCenter.com: Bioinformatics and Comparative Genomics


A wonderful analogy to comparative genomics :)

"Geographic maps are a useful analogy for how we study genomes. If you were given a detailed map of London, you could learn a lot about what defines a large cosmopolitan city. You would see a large number of apartments, shops, and restaurants and might reasonably conclude that these are essential for life in the city. But you could not assess the relative importance of unique features like Buckingham Palace or the Brick Lane street market.

Things would be clearer if you were also given a detailed map of Paris. That too has apartments, shops, and restaurants, confirming your earlier hypothesis. It also has street markets, so perhaps those are an important, albeit secondary, aspect of city life. In contrast, Paris has no "active" royal palaces. Why not? One interpretation might be that Buckingham Palace is an important feature that distinguishes London from other cities. Another might be that a royal family has no function whatsoever in a modern society and survives in London merely as an evolutionary remnant. "

Friday, July 09, 2004

MIT Biological Engineering Division: "Writing DNA: First Synthetic Biology Conference Held at MIT"

The outcome of the Synthetic Biology Conference seams to be the beginnings of a community dedicated on thinking biology in a technology frame of mind.

This would be very useful:
"Endy said that he and his colleagues want to "put in place the technical infrastructure to make routine the design and fabrication of many-component, integrated biological systems."